This is a SAS(r) Software macro package for performing multipoint QTL mapping using the DeFries-Fulker multiple regression approach to unselected and selected samples (basic and augmented) [1] [2] [3], the Haseman-Elston approach [4], and the New Haseman-Elston approach [5].
The latest version of this document is always available at http://qms2.sourceforge.net/ in multipage, single page, PostScript, Portable Document Format, and text formats. The Portable Document Format version is recommended for printing. It requires the freely available Adobe Acrobat software to view.
This document was created using DocBook.
[1] | DeFries, J. C., & Fulker, D. W. (1985). Multiple regression analysis of twin data. Behavior Genetics, 15, 467-473. |
[2] | LaBuda, M. C., DeFries, J. C., & Fulker, D. W. (1986). Multiple regression analysis of twin data obtained from selected samples. Genetic Epidemiology, 3, 425-433. |
[3] | DeFries, J. C., & Fulker, D. W. (1988). Multiple regression analysis of twin data: Etiology of deviant scores versus individual differences. Acta Geneticae Medicae et Gemellologiae, 37, 205-216. |
[4] | Haseman, J. K., & Elston, R. C. (1972). The investigation of linkage between a quantitative trait and a marker locus. Behavior Genetics, 2, 3-19. |
[5] | Haseman, J. K., & Elston, R. C. (in press). Haseman and Elston revisited. Genetic Epidemiology. |